Table 2 Summary of adverse events

From: Thalidomide-based regimen shows promising efficacy in large granular lymphocytic leukemia: a multicenter phase II study

Adverse events

Grade 1 or 2

Grade ≥ 3

 

Number of patients (percent)

Hematological toxicity

 Neutropenia

4 (7.4)

0

Nonhematological toxicity

 Neuropathy: sensory

9 (16.7)

2 (3.7)

 Neuropathy: motor

2 (3.7)

0

 Hyperglycemia

2 (3.7)

0

 Obesity

1 (1.9)

0

 Cushingoid

1 (1.9)

0

 Constipation

3 (5.6)

0

 Alanine/aspartate aminotransferase increased

2 (3.7)

0

 Deep venous thromboembolism

1 (1.9)

0

 Creatinine

0

1 (1.9)

 Arthralgia

0

1 (1.9)

 Osteoporosis

2 (3.7)

0

 Photophobia

1 (1.9)

0

 Fatigue

2 (3.7)

0

 Erectile dysfunction

1 (1.9)

0