Fig. 1

CD38 deficiency alleviated hepatic ischemia-reperfusion injury (HIRI) in mice. a CD38 expressions were determined by Western blotting and quantitative analysis in liver tissues after ischemia/reperfusion (I/R) injury. b The mRNA expressions of IL1B and IL-6 in liver tissues after I/R injury. c Representative fluorescence images of IL-1β/F4/80 and IL-1β/ASGR1 were taken from CD38^KO mice subjected to HIRI, respectively. d, e Serum ALT and AST were measured in CD38^KO and CD38^MKO mice subjected to HIRI. f, g Representative H&E staining images and the quantitative analysis of liver ischemic necrosis were taken from CD38^KO and CD38^MKO mice subjected to HIRI, respectively. Data are shown as means ± SEM, *p < 0.05, **p < 0.01 and ***p < 0.001, n = 3–9 per group