Table 1 Overlapping proteins for neurodegenerative diseases (Top 20)

From: Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury

 

Cortex

Hippocampus

Contralateral

Ipsilateral

Contralateral

Ipsilateral

1H

3H

1H

3H

1H

3H

1H

3H

PD

48 h

-

Cox6a1

Ache- Ibl1

Cox6a1

-

Cox6a1- Apoa1

-

Cox6a1- Apoa1- Snca

1 week

Tfam- Aco2- Gc

Cox6a1 -Tfam- Gc

Tfam

Cox6a1- Psap

-

Cox6a1- Gc

-

Cox6a1- Snca

AD

48 h

Capn1

Rpl35

Aqp4- Rpl35- Ache

Cox6a1- Aqp4- Rpl35- Epha4

Adam10

Cox6a1- Rpl35- Apoa1

Hspa1l

Cox6a1- C3- Rpl35- Apoa1- Ndufb3- Snca

1 week

Nrgn- Tfam- Gc- Sod2

Cox6a1- Rpl35- Ndufa3- Tfam- Gc

Aqp4- Tfam- Nrgn

Cox6a1- Aqp4- Rpl35

-

Cox6a1- Rpl35- Gc

-

Cox6a1- Rpl35- Snca

HD

48 h

-

Ppp1r1b

Ache

-

-

-

-

Ndufb3

1 week

Tfam

Tfam

Tfam

-

-

-

-

-

ALS

48 h

Rpl35

Rpl35

Aqp4- Rpl35

Ap4- Rpl35

-

Rpl35

-

Rpl35

1 week

Tfam- Sod2

Rpl35- Tfam

Aqp4- Tfam

Ap4- Rpl35

-

Rpl35

-

Rpl35

MS

48 h

-

-

Ache

-

-

Apoa1

-

Apoa1

1 week

Gc

Gc

-

-

-

Gc

-

-

Epilepsy

48 h

C1qa

-

Aqp4- Ache

Aqp4

C1qa

-

-

-

1 week

Nrgn

-

Aqp4

Aqp4

-

C1qa

-

C1qa