Fig. 3
From: Dual roles and therapeutic targeting of tumor-associated macrophages in tumor microenvironments
Distribution and density of tumor-associated macrophages in the tumor microenvironment. The spatial distribution of TAMs in tumor tissues, with a focus on the contrasting densities of M1 and M2 TAMs in various tumor regions. The figure shows that M1 TAMs are generally found at higher densities in central tumor regions, promoting antitumor immunity, whereas M2 TAMs are more prevalent in the periphery, assisting in tumor growth and metastasis. (created with Figdraw)
