Table 2 Summary of results from studies using telerehabilitation as an intervention for SCI in LMICs.

From: Telerehabilitation for individuals with spinal cord injury in low-and middle-income countries: a systematic review of the literature

Study

RoB 2 [34]

ROBINS-I [35]

GRADE Quality [36, 37]

 

Results

Outcome measures

Outcome

Statistical significance

Arora et al. [41]

Low

Moderate

 

Mean adjusted between-group difference:

95% CI; p value:

Primary:

Primary:

Primary:

size of PU at 12 weeks (cm2)

2.3

−0.3–4.9; p = 0.08

Secondary:

Secondary:

Secondary:

PUSH score /17

1.8

0.3–3.3; p = 0.02

Depth of PU (cm)

0.2

−0.1–−0.5; p = 0.17

Undermining distance of PU (cm)

0.6

−0.2–1.4; p = 0.14

Braden score (23 points

1.4

0.7–2.0; p < 0.001

Depression items—HADS (21 points)

0.2

−1.1–1.4; p = 0.77

Participation items—WHODAS (40 points)

2.3

0.8–3.8; p = 0.003

Utility score—EQ-5D-5L (units)

0.1

0.02–0.2; p = 0.01

Self-rated health EQ-5D-VAS (100 points)

10.5

4.5–16.6; p = 0.001

Participants' impression of PU status (10 points)

0.8

−0.1–1.7; p = 0.08

Participants' confidence to manage PU (10 points)

1.7

1.0–2.3; p < 0.001

Clinician’s impression of PU status (10 points)

0.6

−0.3–1.4; p = 0.18

Participants' satisfaction (10 points)

2.1

1.3–2.8; p < 0.001

Self-report time for PU resolution

Self-report time for PU resolution

Self-report time for PU resolution

Hossain et al. [42]

Low

Moderate

Primary:

Primary:

Primary: Hazard ratio from unadjusted Cox model

All-cause mortality rate

Intervention group 15/204 (7.4%) died Control group 16/206 (7.8%) died

0.93 (95% CI, 0.46–1.89; p from log rank test 0.85)

Secondary Continuous Outcomes:

Secondary: Continuous Outcomes (Adjusted between-group differences):

Secondary: Continuous Outcomes (95% CI; p value):

SCI-SCS (/40)

−0.3

−0.8–0.3; p = 0.39

PUSH (/17)

−0.2

−0.9–0.6; p = 0.69

CESD-R (/60)

0.0

−2.1–2.1; p = 1.00

WHODAS (/40)

0.2

−0.8–1.2; p = 0.69

SF12 PCS

0.7

−0.3–1.8; p = 0.18

SF12 MCS

−0.1

−2.6–2.4; p = 0.94

SCIM-SR (/100)

1.3

−1.0–3.6; p = 0.27

Binary Outcomes:

Binary Outcomes (Effect calculated with log-binomial regression):

Binary Outcomes: (Adjusted risk ratio)

PU status

0.92

0.56–1.53

Bed-bound

0.80

0.22–2.91

House-bound

0.81

0.52–1.14

Unemployed

1.02

0.92–1.13

Hossain et al. [43]

Unclear

Low

Primary: All-cause mortality rate

Secondary:

SCI secondary conditions scale (/49)

Presence of PU (n)

PUSH (/17)

CES depression scale (/60)

SF12 PCS

SF12 MCS

SCIM (/100)

WHODAS (/40)

Number of days out of bed in past week

Number of days out the house in the past week

Number of days working in the past week

Primary: Intervention group 1/15 (6.7%) died Control group 1/15 (6.7%) died

Secondary: No clear between group differences

No statistical analysis performed

Tyagi et al. [44]

 

Very low

SCIM (/40)

Initial 4 weeks:

Participant 1: 14/40

Participant 2: 5/40

Proceeding 4 weeks (implementation of intervention):

SCIM increased

Participant 1: 27/40

Participant 2: 16/40

No statistical analysis performed

Leochico et al. [45]

 

Very low

Primary: Perspective of telerehabilitation

Quantitative: Numerical questionnaire pre- and post-telerehabilitation intervention

Qualitative: Interview

Primary:

Quantitative: No improvement to score

Qualitative: Perceptions of telerehabilitation improved following telerehabilitation use

No statistical analysis performed

  1. No participant feedback was available in studies which did not perform qualitative interviews or analysis.
  2. SCI spinal cord injury, PU pressure ulcer, ICT information and communication technology, CRP Centre for the Rehabilitation of the Paralysed, FEV1 Forced Expiratory Volume in 1 s, PEF peak expiratory flow, WHOQOL-BREF brief version of WHO quality of life scale, ESES Exercise Self-Efficacy Scale, PUSH Pressure Ulcer Scale for Healing (measures severity of pressure ulcer), HADS Hospital Anxiety and Depression Score, WHODAS World Health Organisation Disability Assessment Schedule (participation over the past 30 days), EQ-5D-5L Euro Quality of Life 5-dimensional 5-level (measures health state), VAS Visual Analogue Scale, SCI-SCS Spinal Cord Injury Secondary Conditions Scale, CESD-R Centre for Epidemiological Studies Depression Scale revised version, PCS Physical Component Score, SF12 Short Form Health Survey-12 (measures health related quality of life), MCS Mental Component Score, SCIM Spinal Cord Independence Measure, MDT multi-disciplinary team, CES Centre for Epidemiological studies.