Fig. 3: Influence of the testing paradigm used on locomotor recovery outcomes and percentage of reporting study quality parameters. | Spinal Cord

Fig. 3: Influence of the testing paradigm used on locomotor recovery outcomes and percentage of reporting study quality parameters.

From: Effectiveness of biomaterial-based combination strategies for spinal cord repair – a systematic review and meta-analysis of preclinical literature

Fig. 3

A Percentage of studies reporting study quality parameters. B Effect of the influence of testing biomaterial properties and performing in vitro and in vivo experiments testing combinations (n = 29) vs. in vivo experiments only (n = 47) on the effect size as a percentage of improvement in motor score. Vertical error bars represent the 95% CI for the individual estimates, and the horizontal shaded grey bar represents the 95% CI of the global estimate. The width of each vertical bar is normalised to the square root of number of animals contributing to that comparison.

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