Table 1 Examples of stem cell and botulin toxin A trials for SCI with inconsistent intervention categorization.
ID | Title | Intervention/Treatment | ClinicalTrials.gov category | Discrepancy | |
|---|---|---|---|---|---|
Stem Cells | |||||
NCT01772810 (USA) | Safety study of human spinal cord-derived neural stem cell transplantation for the treatment of chronic SCI | Human spinal cord stem cells | Drug | Categorized as a drug intervention | |
NCT03505034 (China) | Intrathecal transplantation of UC-MSC in patients with late stage of chronic spinal cord injury | Umbilical cord mesenchymal stem cells | Drug | Categorized as a drug intervention | |
NCT05054803 (Spain) | Cell therapy for chronic traumatic cervical incomplete spinal cord injury | WJ-MSC (XCEL-UMC-BETA) Placebo | Drug Drug | Categorized as a drug intervention | |
NCT01769872 (Korea) | Safety and effect of adipose tissue derived mesenchymal stem cell implantation in patients with spinal cord injury | Autologous adipose tissue derived MSCs (mesenchymal stromal cell) transplantation | Procedure | Categorized as a procedural intervention | |
NCT05671796 (Brazil) | Autologous bone marrow stem cell transplantation in patients with subacute spinal cord injury | Mesenchymal stem cell transplantation Placebo | Genetic Other | Categorized as a genetic intervention Ambiguous categorization | |
Botulin Toxin A | |||||
NCT02660138 (USA) | Dysport® Treatment of urinary incontinence in adults subjects with neurogenic detrusor overactivity (NDO) due to spinal cord injury or multiple sclerosis – Study 1 | Botulinum toxin type A Placebo | Biological Drug | Categorized as a biological intervention Categorized as a drug intervention | |
NCT01911377 (Canada) | Botulinum toxin type A for treating allodynic pain in SCI and MS | Botulinum Toxin Type A Normal saline for injection | Drug Drug | Categorized as a drug intervention Categorized as a drug intervention | |
NCT02052024 (USA) | Myobloc Atrophy study | Botox MYOBLOC | Drug Drug | Categorized as drug interventions | |
