Table 1 Anthropometric and analytical characteristics in the cohort V

From: Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota

Follow-up study (cohort V)

 

Group 1

Group 2

p-Value

∆Ratio P + V/C + O

−1.14 ± 1.29

2.83 ± 3.20

0.002

n

8

11

 

Sex (females/males)

6/2

4/7

0.096

∆Succinate (mM)

−25.19 ± 27.11

12.33 ± 32.75

0.017

∆Weight (kg)

−0.25 (−19.1 to 3.47)

1.8 (−1 to 3.8)

0.351

∆BMI (kg/m2)

0.15 (−3.35 to 1.42)

0.30 (−0.4 to 1.3)

0.840

∆Waist (cm)

8 (−39 to 11)

8 (4.75 to 10.5)

0.475

∆Hip (cm)

2 (−33 to 6)

3 (−0.5 to 3.75)

0.887

∆SBP

−0.71 ± 23.73

3.20 ± 16.56

0.693

∆DBP

−1.71 ± 13.74

6.8 ± 11.50

0.185

∆Glucose (mg/dl)

−1 ± 7.78

6 ± 6.15

0.042

∆Cholesterol (mg/dl)

6.12 ± 30.60

−4.09 ± 22.83

0.415

∆HDL cholesterol (mg/dl)

2.87 ± 12.91

0.55 ± 7.12

0.620

∆Triglycerides (mg/dl)

1.61 ± 21.61

6.63 ± 27.56

0.675

∆Hb1ac (%)

0.41 ± 0.70

0.4 ± 0.68

0.969

∆ Prevotellaceae

−3.66 ± 4.29

6.21 ± 7.68

0.005

∆Veillonellaceae

−0.44 ± 1.89

−0.7 ± 1.38

0.728

∆Odoribacteraceae

ND

ND

–

∆ Clostridaceae

0.26 (−0.66 to 0.44)

−1.1 (−2.82 to –0.58)

0.039

  1. Data are presented as mean ± SD or median (25th–75th), as appropriate. Differences were analyzed by the unpaired t-test (normal distribution) or Mann–Whitney U-test (data not-normally distributed). Group 1 (patients ratio decreases at the end of follow-up) and Group 2 (patients ratio increases at the end of follow-up). A p-value <0.05 was considered significant
  2. BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, ND not detected
  3. Bold values represent those with statistically significant differences
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