Fig. 2: 13C-enrichment of selected metabolites during 13C-bicarbonate dynamic tracing experiments. | The ISME Journal

Fig. 2: 13C-enrichment of selected metabolites during 13C-bicarbonate dynamic tracing experiments.

From: Autotrophic and mixotrophic metabolism of an anammox bacterium revealed by in vivo 13C and 2H metabolic network mapping

Fig. 2

a Mass isotopomer distributions (MID) for selected metabolites illustrating the effects of potential substrate channelling or compartmentation of the Wood–Ljungdahl Pathway and PFOR. b 13C enrichment of metabolites associated with (left) initial CO2 fixation reactions (Wood–Ljungdahl Pathway, pyruvate:ferredoxin oxidoreductase) and metabolites downstream of pyruvate; (centre) TCA cycle metabolites; (right) gluconeogenesis and pentose phosphate pathway metabolites. c Selected mass isotopomer distributions for metabolites of the TCA cycle, gluconeogenesis, and the pentose phosphate pathway. All measured metabolite MIDs represent the average of 3 independent biological replicate experiments. Metabolite MIDs and standard errors can be found in Supplementary Dataset 3.

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