Table 2 Simulation and calculation results under the exposure of non-antibiotic pharmaceuticals.

From: Non-antibiotic pharmaceuticals enhance the transmission of exogenous antibiotic resistance genes through bacterial transformation

Condition

Kμ*

Amplify factor of Kμ*

μ

Kd*

Amplify factor of Kd*

d

Stability time (h)a

Control

0.157

1

1.75 × 10−9

0.936

1

0.0117

178

Ibuprofen

0.856

5.5

9.54 × 10−9

1.109

1.1848

0.0139

148

Naproxen

1.230

7.8

1.37 × 10−8

0.946

1.0107

0.0118

153

Gemfibrozil

2.937

18.7

3.27 × 10−8

0.955

1.0203

0.0119

152

Diclofenac

1.576

10.0

1.76 × 10−8

1.161

1.2404

0.0145

134

Propranolol

2.984

19.0

3.33 × 10−8

1.193

1.2746

0.0149

131

Iopromide

0.395

2.5

4.41 × 10−9

0.969

1.0353

0.0121

171

Combined effect

–

–

–

Product

1.9998

0.0233

105

  1. aThe time reaching 95% of the final theoretical value.
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