Fig. 3: Inhibiting QS increases the fitness of P. aeruginosa in the presence of 106 pfu of phage.

A Relative fitness of sensitive CRISPR-KO strain during competition with the phage resistant surface mutant (sm). B Relative fitness of BIM2 during competition with a phage resistant surface mutant (sm). C Relative fitness of BIM2 during competition with a sensitive CRISPR-KO strain. Box plots show the median, 25th and 75th percentile, and the interquartile range. Raw values from each replicate are shown as points, N = 6. Dotted line in panels (B and C) indicates the point at which competing strains are equally fit (when relative fitness = 1).