Fig. 4: Single gene deletions can substantially alter adaptation through changes to demographic noise.
From: Mutability of demographic noise in microbial range expansions
a Schematic for measurement of establishment probability. After 3 days, the number of beneficial sectors is counted and the establishment probability is calculated by dividing by the initial number of chloramphenicol resistant cells at the expansion front [26]. CmR: chloramphenicol resistance gene. b Interpolated establishment probability at three different fitness coefficients as a function of bead trajectory MSD. Error bars in establishment probability represent linear fitting error (see Supplementary Methods) and error bars in bead MSD represent the standard error of the weighted mean (N = 7–8, see Methods). c Example colonies for two different strain backgrounds each at two fitness coefficients between the resistant and sensitive types.
