Fig. 4: Metabolic traits of the Acidithiobacillia class species.

A Phyletic patterns of relevant energy metabolism genes (and associated gene clusters). Color coding is as labeled in the figure panel. Size of the circles represents the gene dose of representative genes in each cluster. PF variants identified are detailed in Table S7c. B Functional association networks based on gene vicinity concurrence frequencies (edges), including variants per protein family (nodes) as detailed in Table S7c. Concurrence frequency (%) of each gene pair was scored for all genomes from gene annotation tables, at selected relevant genetic contexts. Statistical concurrence information was used to color the edges as indicated in the label and were used to derive functional modules. Additional details can be found in Supplementary Information (Extended Figure Legends).