Fig. 2: Phylogenetic relationship and genomic characterization of Endozoicomonas genomes.

A Phylogenetic placement of the novel Endozoicomonas marisrubri 6c isolate (highlighted in turquoise) from the Red Sea coral Acropora humilis. The unrooted species tree was generated through the OrthoFinder2 default workflow and visualized in FigTree v1.1.4 [61]. Vertical bars show the two clades of Endozoicomonas and respective genome sizes (purple; asterisks refer to genomes of ≤90% completeness), boxes indicate G+C content (in %; blue hues), and coding density (in %; yellow hues) of the respective genomes. B Distribution of genes and functions proposed to be involved in symbiotic establishment and maintenance across Endozoicomonas clades and genomes according to their associated gene families (ortholog clusters) and Pfam profiles. The color code used for ankyrins, serpins, and ephrins from turquoise to red reflects the number of genes per million base pairs (Mbp) of genome. Black boxes for genes associated with B vitamin biosynthetic gene clusters reflect their presence within the respective genome. C Distribution of protein domains associated with DMSP catabolism across Endozoicomonas genomes based on annotation with Prokka, KEGG, and UniProt. Black boxes reflect the presence of protein domains within the respective genome.