Fig. 6: Schematic overview of the potential metabolism of the marine parasite Amoebophrya inside its microalgal dinoflagellate host Scrippsiella acuminata underlying major metabolic shifts.

Major metabolic pathways have been displayed where the color of individual enzymes indicates the stage with maximum expression of their genes: yellow for intracellular parasites; blue in dinospores (free-living stage); gray whereby no difference in expression between the two stages. Dashed lines represent transport of various components; filled lines represent enzymatic reactions. Coenzymes are color-coded as purple: adenosine bi- and triphosphate (ADP and ATP, respectively); nicotinamide adenine dinucleotide phosphate (NAD(P)H); coenzyme A (CoA); quinone pool (Q and QH₂). The putative location of one of the NADH:ubiquinone oxidoreductase (NDH1b/CI’) complexes, the hexose transporter (HT1) and Sugars Will Eventually be Exported Transporter (SWEET) are depicted by yellow. A question mark in the tricarboxylic acid cycle (TCA) illustrates the apparent loss of the oxoglutarate dehydrogenase/ (OGDC) or α-ketoglutarate dehydrogenase complex in Amoebophrya. Invagination of the cytoplasm to form a cytopharynx is represented to illustrate captured host chromosome to be digested in vacuoles. The list of genes, their sequences and expression values can be found in Table S2.