Fig. 2: MIC values observed for 10 strains of the EM genogroup (all lacking the D87Y gyrA point mutation, Psal-069 displayed a ciprofloxacin-resistant phenotype), and ten strains of the LF genogroup (Psal-008 lacking the gyrA point mutation).

Psal-069 also did not exhibit any other known resistance mechanisms: mutations in gyrB, in parC, and parE encoding topoisomerase IV, presence of gyrase-protecting Qnr proteins, acetyltransferases, or high expression through mutations in promoter regions of efflux pumps [74].