Table 1 Baseline patient characteristicsa
rTMS + ADP (n = 82) | rTMS (n = 91) | ADP (n = 108) | |
|---|---|---|---|
Demographic characteristics | |||
Female, n (%) | 60 (73.2) | 66 (72.5) | 85 (78.7) |
Han ethnic origin, n (%) | 82 (100) | 91 (100) | 108 (100) |
Age, years | |||
Mean ± SD | 42.3 ± 11.4 | 40.0 ± 11.5 | 40.9 ± 11.8 |
Range | 19–63 | 19–64 | 18–64 |
Marital status | |||
Single, separated/divorced and widowed, n (%) | 14 (17.1) | 14 (15.4) | 17 (15.7) |
Married, n (%) | 68 (82.9) | 77 (84.6) | 91(84.3) |
Education | |||
Illiterate and elementary, n (%) | 4 (4.8) | 3 (3.3) | 7 (6.5) |
Middle, n (%) | 24 (29.3) | 24 (26.4) | 36 (33.3) |
High, n (%) | 24 (29.3) | 28 (30.7) | 23 (21.3) |
College and above, n (%) | 30 (36.6) | 36 (39.6) | 42 (38.9) |
Employment status | |||
Students, unemployed and retired, n (%) | 34 (41.5) | 36 (39.6) | 36 (33.3) |
Employed, n (%) | 48 (58.5) | 55 (60.4) | 72 (66.7) |
Clinical characteristics | |||
Family history of mental illness, n (%) | 8 (9.7) | 2 (2.2) | 2 (1.9) |
Duration of the illness, months | |||
Mean ± SD | 14.5 ± 20.1 | 10.2 ± 11.3 | 14.2 ± 22.8 |
Range | 1–120 | 1–60 | 1–120 |
No. of previous depressive episode | |||
0 (first episode), n (%) | 51 (62.2) | 52 (57.1) | 73 (67.6) |
1, n (%) | 3 (3.7) | 11 (12.1) | 6 (5.6) |
2–4, n (%) | 22 (26.8) | 27 (29.7) | 26 (24.1) |
≥5, n (%) | 6 (7.3) | 1 (1.1) | 3 (2.8)3 |
Antidepressants taken in run-in treatmentb | |||
Paroxetine | 53 (64.6) | 60 (65.9) | 78 (72.2) |
Venlafaxine | 8 (9.8) | 18 (19.8) | 19 (17.6) |
Escitalopram | 7 (8.5) | 6 (6.6) | 9 (8.3) |
Fluoxetine | 12 (14.6) | 4 (4.4) | 2 (1.9) |
Sertraline | 2 (2.5) | 3 (3.3) | 0 |
Symptom severity at entry into run-in treatment | |||
HAMD-17, mean ± SD | 22.9 ± 3.6 | 24.1 ± 3.6 | 24.0 ± 3.5 |
CGI-S, mean (SD) | 4.5 ± 0.7 | 4.4 ± 0.7 | 4.5 ± 0.7 |
Symptom severity at entry into maintenance treatment | |||
HAMD-17, mean ± SD | 6.5 ± 2.2 | 5.9 ± 3.0 | 5.8 ± 4.1 |
CGI-S, mean ± SD | 1.3 ± 0.5 | 1.2 ± 0.4 | 1.3 ± 0.6 |
Remission | |||
Full (HAMD-17 ≤ 7), n (%) | 55 (67.1) | 73 (80.2) | 85 (78.7) |
Partial (HAMD-17 = 8–14), n (%) | 27 (32.9) | 18 (19.8) | 23 (21.3) |
