Fig. 2: Influence of different types of stress on depression- and anxiety-like behavior

a–d Body weight changes in the chronic unpredictable mild stress (CUMS), learned helplessness (LH), chronic restraint stress (CRS), and social defeat (SD) models. e–h Sucrose preference changes in the CUMS, LH, CRS, and SD models. i Immobility time of the four models in the forced swimming test. j–l Total distance, central activity, and rearing frequency of the four models in the open field test. m–p Total number of entries into and time spent in the open and closed arms of the four models in the elevated plus-maze. *P < 0.05, **P < 0.01, ***P < 0.001