Fig. 1: Diet impacts multiple measures of the diffusion tensor in a diet-dependent manner. | Translational Psychiatry

Fig. 1: Diet impacts multiple measures of the diffusion tensor in a diet-dependent manner.

From: Gut microbiome populations are associated with structure-specific changes in white matter architecture

Fig. 1

Ex-vivo diffusion tensor imaging (DTI) was performed 21 days after immediately post-weaned male rats were assigned to one of four assigned diets (n = 20; n = 5 in each diet group) to measure diet-dependent changes in the diffusion tensor when referenced to control animals. Following tract-based spatial statistics (TBSS) analysis, areas of increased FA (a, b) and decreased trace (TR) (c, d) axial (AD) (e, f) and radial diffusivity (RD) (g, h) for each experimental diet group (as compared to the standard diet) were identified and are displayed over masked oblique and coronal fractional anisotropy (FA) maps. No voxels corresponding to decreased FA or increased TR, AD, or RD were identified. Areas highlighted in yellow (high fat), green (high fiber), and magenta (high protein, low carbohydrate) represent diet-specific voxels where tract-based spatial statistics (TBSS) analysis revealed statistically significant diffusion tensor differences between each of the enriched diet groups and the control diet group. No significant changes were found in FA for the fat diet group or in AD for the fiber diet group

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