Fig. 1: Loci with multiple independent signals of association | Translational Psychiatry

Fig. 1: Loci with multiple independent signals of association

From: Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data

Fig. 1

The plots show the results for the joint and conditional analysis with merged Norwegian and German cohorts as the LD reference sample for the loci on chromosome 18 (a) and chromosome 22 (b). On each plot, several independent signals are identified using the stepwise procedure within a 10 Mb window in cojo-GCTA. SNPs are plotted according to their chromosomal positions based on UCSC hg19/NCBI build 37. The –log10(p values) of the SNPs are shown on each plot. LD values between the lead SNP and the other markers are indicated by color. Genes located in the region of interest are indicated at the bottom. Plots were generated using the LocusZoom tool34

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