Table 1 Summary statistics for SNPs with association P-value ≤ 1 × 10−6 for depression (MDD), recurrent depression (rMDD), depression in females only (fMDD) and depression in males only (mMDD), sorted within phenotype by genomic positions according to UCSC hg19/NCBI Build 37
From: Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank
Trait | SNP | CHR | POS | A1/A2 | Freq | β(se) | P | Direction | Genes |
|---|---|---|---|---|---|---|---|---|---|
MDD | rs56390503 | 4 | 187552576 | T/C | 0.11 | 0.13 (0.03) | 9.08E–07 | ++ | FAT1 |
rs2964802 | 5 | 10820843 | T/C | 0.28 | 0.09 (0.02) | 6.73E–07 | ++ | - | |
rs11033303 | 11 | 35871266 | A/G | 0.37 | 0.09 (0.02) | 2.37E–07 | ++ | - | |
rMDD | rs2291479 | 3 | 178174944 | A/C | 0.4 | −0.10 (0.02) | 9.65E–07 | -- | - |
rs10959631 | 9 | 11220986 | T/C | 0.2 | −0.12 (0.02) | 8.34E-07 | -- | - | |
rs11033303 | 11 | 35871266 | A/G | 0.37 | 0.11 (0.02) | 6.02E–07 | ++ | - | |
rs4438172 | 13 | 111448658 | A/T | 0.25 | 0.11 (0.02) | 8.72E–07 | ++ | - | |
fMDD | rs9648182 | 7 | 13794849 | A/T | 0.12 | −0.17 (0.03) | 9.14E–08 | -- | - |
rs17176546 | 7 | 81880914 | A/G | 0.04 | 0.26 (0.05) | 7.93E–07 | ++ | CACNA2D1 | |
mMDD | rs115736167 | 1 | 155266609 | C/G | 0.02 | −0.46 (0.09) | 1.54E–07 | -- | PKLR |
rs4478037 | 3 | 33160407 | A/G | 0.08 | 0.29 (0.05) | 2.29E–08 | ++ | CRTAP | |
rs113485090 | 11 | 73572495 | A/G | 0.04 | -0.32 (0.06) | 2.05E-07 | -- | MRPL48 | |
rs1380551 | 15 | 24124704 | A/G | 0.15 | -0.18 (0.04) | 3.96E-07 | -- | - |
