Fig. 1: Enrichment and −log10 P-value for the results of partitioned heritability analysis for SNPs within H3K4me3 marks (a marker of active gene promoters) for the different cell types
From: Enrichment of schizophrenia heritability in both neuronal and glia cell regulatory elements
. a Enrichment of schizophrenia heritability at H3K4me3 sites in post-mortem brain tissues. Y-axis is the enrichment value and x-axis is the different cell types. b −log10 P-values for the enrichment of schizophrenia heritability at H3K4me3 sites in post-mortem brain tissues. X-axis is the −log10 P-value derived from the z-score; y-axis is the different cell types. Red line is the significance threshold for a Bonferroni correction for multiple testing for total number of analyses undertaken (14 tests performed). c Enrichment of schizophrenia heritability at H3K4me3 sites identified in cultured cells. Y-axis is the enrichment value and x-axis is the different cell types. d −log10 P-values for enrichment of schizophrenia heritability at H3K4me3 sites identified in cultured cells. X-axis is the −log10 P-value derived from the z-score; y-axis is the different cell types Red line is the significance threshold for a Bonferroni correction for multiple testing for total number of analyses undertaken (14 tests performed)
