Fig. 1: The effects of tDCS and DBS on repetitive behavior | Translational Psychiatry

Fig. 1: The effects of tDCS and DBS on repetitive behavior

From: Non-invasive modulation reduces repetitive behavior in a rat model through the sensorimotor cortico-striatal circuit

Fig. 1

a tDCS (anodal/cathodal at 100 , 200  or 300  µA) effects on the occurrence of oral stereotypy in the DAT-tg rats in relation to sham stimulation. b Effect of tDCS (anodal/cathodal at 100 , 200 or 300  µA) on the occurrence of head movements in the wt rats in relation to sham stimulation. c Low- and high-frequency DBS (mPFC, OFC, M1, Thal and CPu) effects on the occurrence of oral stereotypy in the DAT-tg rats in relation to sham stimulation. d Low- and high-frequency DBS (mPFC, OFC, M1, Thal and CPu) effects on the occurrence of oral stereotypy in the wt rats in relation to sham. wt wild-type rats, DAT-tg dopamine transporter-overexpressing rats, mPFC medial prefrontal cortex, OFC orbitofrontal cortex, M1 primary motor cortex, Thal thalamus, CPu caudate putamen. All data are given as mean ± s.e.m. Asterisks (*) indicate significant differences between stimulation conditions with p < 0.05

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