Fig. 1: Z-score statistical map of significant baseline comparison in functional connectivity between control subjects and first-episode mania patients collapsed across both treatment groups; quetiapine and lithium.

DC dorsal caudate nucleus, DP dorsal putamen, VS ventral striatum including the nucleus accumbens. R right hemisphere. Insets show results overlaid on glass brain. Results are displayed at P < 0.05 (FWE cluster corrected). For more information see Supplementary Materials