Fig. 1: Experimental setup. | Translational Psychiatry

Fig. 1: Experimental setup.

From: Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals

Fig. 1

The experimental paradigm described by Normann et al.28 was used at baseline, as described previously, and at follow-up. VEPs were evoked by checkerboard reversals (check size = 0.5°; 2 reversals/sec) in two premodulation blocks before and six blocks after a plasticity-inducing modulation block consisting of 10 min of checkerboard reversal stimulation (check size = 0.5°; 2 reversals/sec). The premodulation blocks were initiated 2 and 8 min after the start of the experiment, and the modulation block was initiated 2 min after the last premodulation block. The postmodulation blocks were performed 2, 8, 12, 18, 22, and 28 min after the end of the modulation block. A gray screen was displayed in the intervals between checkerboard stimulation. Participants were instructed to focus on a filled red circle (0.1°) in the center of the screen during the experiment and were allowed to listen to music. The participants were monitored throughout the experiment to ensure that they followed instructions and maintained attention. VEP, visual evoked potential

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