Fig. 3: Saliva cortisol and VEP plasticity. | Translational Psychiatry

Fig. 3: Saliva cortisol and VEP plasticity.

From: Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals

Fig. 3

a Saliva cortisol was collected the day after the VEP experiment at three times: immediately after awakening in the morning, 30 min after the first collection, and at 12:30 PM. Saliva cortisol was averaged across the three collections and was significantly increased in patients with BD type II relative to controls. b In controls, there was a significant positive correlation between saliva cortisol and plasticity of the P1–N1 amplitude, indicating greater plasticity with higher cortisol levels. c There was also a significant positive correlation between the cortisol awakening response and plasticity of the P1–N1 amplitude in controls. VEP, visual evoked potential. BD, bipolar disorder

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