Table 2 Results of the image analysis

From: Relationship between white matter integrity and serum inflammatory cytokine levels in drug-naive patients with major depressive disorder: diffusion tensor imaging study using tract-based spatial statistics

    

MNI coordinates, mm

Anatomical regions

Cluster size

p-valuea

t-value

x

y

z

FA values, between-group comparison (control group > MDD group)

lt. ATR (11.139), lt. IFOF(9.479)

1951

0.033

3.34

114

156

79

lt. CT (7.286)

1427

0.032

3.80

109

108

111

FM (18.098), rt. IFOF (7.698)

1272

0.033

5.44

63

158

90

rt. CT (22.695)

328

0.039

3.92

67

94

114

Negative correlation between FA values and IL-1β levels in the MDD group

FM (2.741), rt. IFOF (2.567)

27510

0.993

3.43

113

50

92

lt. IFOF (1.127), lt. UF (4.403)

362

0.955

3.91

96

142

61

Interaction of IL-1β level in the control group and MDD group

lt. ATR (0.591), lt. IFOF(2.588),

lt. CT (0.638), rt. CT (1.265),

FM (3.624), lt. UF (0.838),

lt. ILF (2.588), rt. ILF (1.194)

26781

0.009

2.37

−26

−77

1

lt. ATR (16.101)

574

0.039

3.49

−19

−13

−3

  1. Numbers in parentheses are the probability of fiber tracts
  2. MNI Montreal Neuroglogic Institute, MDD major depressive disorder, rt. right, lt. left, FA fractional anisotropy, ATR anterior thalamic radiation, CTC corticospinal tract, IFOF inferior fronto-occipital fasciculus, ILF inferior longitudinal fasciculus, FM forceps minor, including genu of corpus callosum, UF unicinate fasciculus
  3. awith family-wise error correction
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