Fig. 2: Systems analysis of differential metabolites in MDD subjects and healthy controls. | Translational Psychiatry

Fig. 2: Systems analysis of differential metabolites in MDD subjects and healthy controls.

From: Diagnosis of major depressive disorder based on changes in multiple plasma neurotransmitters: a targeted metabolomics study

Fig. 2

a The correlation heatmap displays the correlation coefficients (Spearman) among differential metabolites. The color-coded scale of correlation is at the bottom, where a blue color indicates a positive correlation, while a red color indicates a negative correlation. b–d ROC curve of GABAergic, catecholaminergic, and serotonergic pathway. neurometabolite symbols with red were upregulated while blue were downregulated in MDD subjects compared with healthy controls

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