Table 3 Differences in the clinical presentation of benzodiazepine withdrawal catatonia and clozapine withdrawal catatonia

From: Review of withdrawal catatonia: what does this reveal about clozapine?

 

Benzodiazepine withdrawal catatonia

Clozapine withdrawal catatonia

Dose of treatment

Average-high (benzodiazepine dose)

Average (clozapine dose)

Duration of treatment

Long term

Long term

Accompanying psychotic symptoms

Prevalent

Very prevalent

Response rate to treatment with benzodiazepines

High

Low

Most effective treatments

Benzodiazepines

Clozapine, ECT

Time to response

Minutes to hours

Days to weeks