Fig. 5
From: Lithium as a disease-modifying agent for prion diseases

a Immunohistological analysis of LC3 expression (representative images). b, c Quantification of LC3-positive cells (mean ± SEM) in the striatum and cortex, respectively (n = 2 control; n = 5 NP03-40; n = 6 NP03-160; n = 7 lithium-gavage, for striatum; and n = 2 control; n = 5 NP03-40; n = 5 NP03-160; n = 5 lithium-gavage, for cortex). The unpaired Mann–Whitney test was used for statistical analysis in all cases. d, e Individual LC3 levels as a function of the survival time. Scale bar 400 µm