Fig. 2: Association of polygenic risk scores for multiple traits with bipolar disorder (broad extended phenotype) in ASMAD. | Translational Psychiatry

Fig. 2: Association of polygenic risk scores for multiple traits with bipolar disorder (broad extended phenotype) in ASMAD.

From: Genetic pleiotropy between mood disorders, metabolic, and endocrine traits in a multigenerational pedigree

Fig. 2

a Risk scores for all traits tested are displayed, split by the trait type. Circles indicate the association of the risk scores with mood disorder in the ASMAD pedigree, color of circles shows the level of significance, and error bars show ±standard error. b Correlation of risk scores with bipolar disorder risk score within the ASMAD population. Color represents strength and direction of correlation (red – positive, blue – negative). Number in each square is the correlation coefficient (r)

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