Table 1 Clinical variables

From: Brain monoamine oxidase A in seasonal affective disorder and treatment with bright light therapy

 

SAD

 

HC

BDI (PET1)

BLT

17.08 ± 5.63*

**

0.83 ± 1.40

Placebo

11.91 ± 5.86

1.38 ± 2.10

BDI (PET2)

BLT

11.17 ± 7.27***

**

0.92 ± 1.78

Placebo

7.75 ± 5.65

0.21 ± 0.58***

BDI (PET3)

BLT

4.27 ± 3.47***

**

0.70 ± 1.16

Placebo

2.29 ± 2.69***

0.77 ± 1.53

HAMD (PET1)

BLT

11.15 ± 3.80

**

0.25 ± 0.45

Placebo

8.91 ± 4.55

0.23 ± 0.60

HAMD (PET2)

BLT

9.23 ± 6.87

**

0.5 ± 1.17

Placebo

5.75 ± 4.17

0.14 ± 0.36

HAMD (PET3)

BLT

3.00 ± 3.61

**,***

1.10 ± 1.45

Placebo

2.71 ± 2.93

0.23 ± 0.44

Group size

24

 

27

Age at baseline (mean years±SD)

34.21 ± 10.57

33.52 ± 10.57

Sex (male/female)

8/16

11/16

Therapy arm (BLT/placebo)

13/11

12/15

  1. SAD: seasonal affective disorder, HC: healthy controls, PET: positron emission tomography, BLT: bright light therapy, BDI: Beck Depression Inventory, HAMD: Hamilton Depression Rating Scale
  2. *Significant difference vs. placebo (p < 0.050)
  3. **Significant difference vs. HC (p < 0.010)
  4. ***Significant difference vs. PET1 (p < 0.050)
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