Table 2 Differentially expressed lncRNA distal gene targets and associated GO terms in the Blue and Brown modules
From: Global long non-coding RNA expression in the rostral anterior cingulate cortex of depressed suicides
LncRNA | Gene target | Weight | Associated GO | GO class | GO Description |
|---|---|---|---|---|---|
CTC-487M23.5 (Blue module) | KANK1 | 0.228 | GO:0007155 | BP | Cell adhesion |
GO:0032956 | BP | Regulation of actin cytoskeleton organiz… | |||
GO:0005886 | CC | Plasma membrane | |||
DOCK1 | 0.212 | GO:0043547 | BP | Positive regulation of GTPase activity | |
FNBP1 | 0.212 | GO:0005886 | CC | Plasma membrane | |
CTD-2647L4.4 (Blue module) | YWHAH | 0.229 | GO:0003779 | MF | Actin binding |
GO:0005886 | CC | Plasma membrane | |||
RP11-453F18_B.1 (Blue module) | KANK1 | 0.204 | GO:0007155 | BP | Cell adhesion |
GO:0032956 | BP | Regulation of actin cytoskeleton organiz… | |||
GO:0005886 | CC | Plasma membrane | |||
TJP1 | 0.199 | GO:0016324 | CC | Apical plasma membrane | |
GO:0005886 | CC | Plasma membrane | |||
DOCK1 | 0.212 | GO:0043547 | BP | Positive regulation of GTPase activity | |
FNBP1 | 0.211 | GO:0005886 | CC | Plasma membrane | |
RP11-273G15.2 (Blue module) | TCF12 | 0.165 | GO:0071837 | MF | HMG box domain binding |
GM2A | 0.154 | GO:0005887 | CC | Integral component of plasma membrane | |
GO:0005886 | CC | Plasma membrane | |||
GO:0016021 | CC | Integral component of membrane | |||
SNCB | 0.155 | GO:0005509 | MF | Calcium ion binding | |
YES1 | 0.156 | GO:0007155 | BP | Cell adhesion | |
GO:0005886 | CC | Plasma membrane | |||
GO:0015629 | CC | Actin cytoskeleton | |||
VAMP3 | 0.152 | GO:0007155 | BP | Cell adhesion | |
GO:0005886 | CC | Plasma membrane | |||
GO:0016324 | CC | Apical plasma membrane | |||
GO:0009986 | CC | Cell surface | |||
GO:0016021 | CC | Integral component of membrane | |||
RDX | 0.154 | GO:0003779 | MF | Actin binding | |
GO:0007155 | BP | Cell adhesion | |||
GO:0032956 | BP | Regulation of actin cytoskeleton organiz… | |||
GO:0030027 | CC | Lamellipodium | |||
GO:0016324 | CC | Apical plasma membrane | |||
GO:0005615 | CC | Extracellular space | |||
GO:0015629 | CC | Actin cytoskeleton | |||
RUSC1 | 0.165 | GO:0003779 | MF | Actin binding | |
GO:0005886 | CC | Plasma membrane | |||
RP11-326I11.3 (Blue module) | TJP1 | 0.200 | GO:0016324 | CC | Apical plasma membrane |
GO:0005886 | CC | Plasma membrane | |||
DOCK1 | 0.199 | GO:0043547 | BP | Positive regulation of GTPase activity | |
FNBP1 | 0.220 | GO:0005886 | CC | Plasma membrane | |
YWHAH | 0.193 | GO:0003779 | MF | Actin binding | |
GO:0005886 | CC | Plasma membrane | |||
RP1-269M15.3 (Blue module) | SGPL1 | 0.191 | GO:0016021 | CC | Integral component of membrane |
KANK1 | 0.222 | GO:0007155 | BP | Cell adhesion | |
GO:0032956 | BP | Regulation of actin cytoskeleton organiz… | |||
GO:0005886 | CC | Plasma membrane | |||
DOCK1 | 0.198 | GO:0043547 | BP | Positive regulation of GTPase activity | |
PPFIA1 | 0.195 | GO:0007155 | BP | Cell adhesion | |
GO:0032956 | BP | Regulation of actin cytoskeleton organiz… | |||
WASF2 | 0.189 | GO:0003779 | MF | Actin binding | |
GO:0032956 | BP | Regulation of actin cytoskeleton organiz… | |||
GO:0030027 | CC | Lamellipodium | |||
GO:0015629 | CC | Actin cytoskeleton | |||
RP11-434C1.1 (Brown module) | CELSR3 | 0.130 | GO:0046872 | MF | Metal ion binding |
ATG3 | 0.122 | GO:0016567 | BP | Protein ubiquitination | |
SRRM4 | 0.128 | GO:0005634 | CC | Nucleus | |
DEK | 0.122 | GO:0003677 | MF | DNA binding | |
GO:0006355 | BP | Regulation of transcription, DNA-templat… | |||
GO:0005634 | CC | Nucleus | |||
GRIN1 | 0.124 | GO:0046872 | MF | Metal ion binding | |
GO:0006355 | BP | Regulation of transcription, DNA-templat… | |||
GO:0050773 | BP | Regulation of dendrite development | |||
GO:0048813 | BP | Dendrite morphogenesis |
