Table 2 The characteristics of RCTs

From: Subclinical hypothyroidism and depression: a meta-analysis

First author

Year

Country

N

TSH cut-off mIU/l

fT4 reference pmol/l

Depression test

Intervention

Parle

2010

UK

94

5.5

9.0–20.0

HADS

Initial dosage being 25 ug of L-T4 or placebo per day

Vaneska

2012

Brazil

57

4.0

11.6–23.2

BDI

Initial dosage of L-T4 based on TSH values from 25 µg to 75 µg or placebo per day

Laily

2015

Iran

60

4.5

10.3–25.8

BDI

Received 100 µg of L-T4 (Iran Hormone Product) or placebo per day

Rolf

2006

Norway

69

4.2

9–22

BDI

Dosage of L-T4 based on TSH values from 25 µg to 175 µg or placebo per day