Table 2 The characteristics of RCTs
From: Subclinical hypothyroidism and depression: a meta-analysis
First author | Year | Country | N | TSH cut-off mIU/l | fT4 reference pmol/l | Depression test | Intervention |
---|---|---|---|---|---|---|---|
Parle | 2010 | UK | 94 | 5.5 | 9.0–20.0 | HADS | Initial dosage being 25 ug of L-T4 or placebo per day |
Vaneska | 2012 | Brazil | 57 | 4.0 | 11.6–23.2 | BDI | Initial dosage of L-T4 based on TSH values from 25 µg to 75 µg or placebo per day |
Laily | 2015 | Iran | 60 | 4.5 | 10.3–25.8 | BDI | Received 100 µg of L-T4 (Iran Hormone Product) or placebo per day |
Rolf | 2006 | Norway | 69 | 4.2 | 9–22 | BDI | Dosage of L-T4 based on TSH values from 25 µg to 175 µg or placebo per day |