Fig. 2: Aberrant PKC activation impaired neurogenesis. | Translational Psychiatry

Fig. 2: Aberrant PKC activation impaired neurogenesis.

From: Developmental protein kinase C hyper-activation results in microcephaly and behavioral abnormalities in zebrafish

Fig. 2

a, b Reduced mitotic cells in zebrafish head (3 dpf). a Fluorescence of pHH3-positive dots (the upper row) merged with brightfield images of zebrafish head (the lower row) (n = 26 per group, ***p < 0.001, t-test). Scale bar, 100 μm. c Flow cytometry analysis of the different populations of cells. d Newborn neurons (Q2) are significantly reduced in PMA-exposed fish (n = 9 per group, p < 0.001, t-test)

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