Fig. 2: Neurogenesis, but not astrogenesis, was decreased by nPM exposure in the DG. | Translational Psychiatry

Fig. 2: Neurogenesis, but not astrogenesis, was decreased by nPM exposure in the DG.

From: Prenatal and early life exposure to air pollution induced hippocampal vascular leakage and impaired neurogenesis in association with behavioral deficits

Fig. 2

a Neurogenesis was decreased 70% (p < 0.0001). Astrogenesis was unchanged. b Representative images of EdU staining in the granule cell layer of the DG. Clockwise, from upper left: NeuN staining; GFAP staining; EdU-positive cells, arrows show neurons in green (NeuN) and astrocytes in blue (GFAP); colocalization of EdU-positive cells with GFAP and NeuN immunostaining. Scale bar = 100 μm. Mean ± SEM; ****p < 0.0001. DG dentate gyrus, EdU 5-ethynyl-2′-deoxyuridine, GFAP glial fibrillary acidic protein, MO molecular layer, NeuN neuron nuclear antigen, PO polymorphic layer, GCL granule cell layer

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