Table 2 Top gene set enrichment for WGCNA modules
Module | Top KEGG pathway | FDR | Top GO-terma | FDR |
|---|---|---|---|---|
Baseline | ||||
Black | hsa05162: Measles | 2.0 × 10−8 | 0051607: Defense response to virus | 5.2 × 10−17 |
Blue | hsa04141: Protein processing in ER | 5.4 × 10−66 | 0006888: ER to Golgi vesicle transport | 5.3 × 10−30 |
Brown | hsa03010: Ribosomeb | 2.3 × 10−110 | 0006614: SRP protein targeting to ERc | 4.0 × 10−141 |
Green | hsa04668: TNF signaling | 9.6 × 10−12 | 0006954: Inflammatory response | 9.7 × 10−9 |
Green-Yellow | hsa04110: Cell cycle | 1.2 × 10−20 | 0051301: Cell division | 1.2 × 10−32 |
Magenta | hsa03008: Ribosome biogenesis | 4.3 × 10−12 | 0044822: Poly(A) RNA binding | 1.5 × 10−72 |
Purple | hsa04960: Sodium reabsorption | 0.63 | 0005201: Extracellular matrix structure | 0.18 |
DA-stimulated | ||||
Black | hsa04961: Endocrinal calcium reabsorption | 0.014 | 0007165: Signal transduction | 0.011 |
Blue | hsa04141: Protein processing in ER | 3.1 × 10−48 | 0036498: IRE1-mediated protein response | 4.4 × 10−21 |
Brown | hsa03010: Ribosome | 1.1 × 10−125 | 0006614: SRP protein targeting to ER | 2.7 × 10−161 |
Green | hsa04064: NF-kappa B signaling | 4.1 × 10−8 | 0006954: Inflammatory response | 6.4 × 10−6 |
Green-Yellow | hsa04110: Cell cycle | 1.3 × 10−14 | 0051301: Cell division | 1.2 × 10−44 |
Magenta | hsa04612: Antigen processing | 0.037 | 0044822: Poly(A) RNA binding | 2.6 × 10−24 |
