Table 2 Clinical score comparisons between individual patient subtypes

From: Stratification and prediction of remission in first-episode psychosis patients: the OPTiMiSE cohort study

Clinical scores

C1A versus others

C1B versus others

C2A versus others

C2B versus others

C1A

Others

P value

C1B

Others

P value

C2A

Others

P value

C2B

Others

P value

PPANSS

24.56 ± 0.42

17.84 ± 0.33

<0.0001

17.21 ± 0.55

20.46 ± 0.36

<0.0001

21.29 ± 0.43

19.26 ± 0.40

0.002

13.97 ± 0.38

21.54 ± 0.32

<0.0001

NPANSS

25.72 ± 0.50

17.00 ± 0.42

<0.0001

24.92 ± 0.49

18.35 ± 0.44

<0.0001

14.48 ± 0.42

21.66 ± 0.47

<0.0001

13.49 ± 0.47

21.38 ± 0.43

<0.0001

GPANSS

47.77 ± 0.69

34.06 ± 0.51

<0.0001

37.52 ± 0.89

38.3 ± 0.64

0.52

36.86 ± 0.65

38.67 ± 0.71

0.14

27.55 ± 0.69

41.22 ± 0.53

<0.0001

PANSS total

98.05 ± 1.27

68.9 ± 0.92

<0.0001

79.65 ± 1.25

77.12 ± 1.27

0.18

72.63 ± 1.01

79.59 ± 1.40

0.00

55.01 ± 1.12

84.14 ± 0.99

<0.0001

PSP

44.98 ± 1.35

50.6 ± 1.05

0.001

44.90 ± 2.0

49.61 ± 0.94

0.03

47.56 ± 1.48

49.44 ± 1.04

0.47

59.24 ± 1.71

45.91 ± 0.90

<0.0001

CGI

5.98 ± 0.07

5.23 ± 0.06

<0.0001

5.52 ± 0.11

5.443 ± 0.06

0.69

5.63 ± 0.08

5.39 ± 0.07

0.05

4.472 ± 0.09

5.738 ± 0.05

<0.0001

CDSS

14.12 ± 1.55

12.82 ± 0.29

0.03

13.02 ± 0.61

13.25 ± 0.29

0.82

13.65. ± 0.49

13.03. ± 0.32

0.17

11.59 ± 0.39

13.67 ± 0.32

0.0003

  1. Data show clinical scores (mean ± SEM) of the indicated patients before treatment as well as the statistical significance of the observed differences measured by the p value
  2. PANSS Positive and Negative Syndrome Scale, PPANSS positive PANSS, NPANSS negative PANSS, GPANSS general psychopathology PANSS, CDSS Calgary Depression Scale for Schizophrenia, PSP Personal and Social Performance Scale, CGI Clinical Global Impression