Fig. 2: Human GeneMANIA gene network.

The glucocorticoid receptor (GR)-dependent expression quantitative trait loci (eQTL) network comprises risk genes for major depressive disorder (MDD; gray filled circles, n = 20), schizophrenia (SCZ; black filled circles, n = 39) and both (gray circles with black border, n = 4). It forms a tightly interconnected gene network termed GCN. The edge colors indicate the type of interaction, as explained in the legend on the top left. Information on individual risk genes is provided in Supplemental Table 1