Fig. 3: Ovariectomy (OVX) females have significantly higher angiotensin II type I receptor (AT1R) ligand binding in the anterior pituitary gland and ventral subiculum compared with intact proestrus females.
From: Estradiol modulation of the renin–angiotensin system and the regulation of fear extinction
No significant differences were found between intact proestrus females (♀HI E2; PRO) and any other treatment group (n = 7–17/group) in the a anterior piriform cortex, b posterior piriform cortex, or c basolateral amygdala (BLA). d Males (♂) had a trend for increased AT1R binding in the PVN compared with intact PRO females. e OVX females had significantly higher AT1R ligand binding in the anterior pituitary gland and f ventral subiculum compared with intact PRO females. Representative autoradiograms from a high estradiol proestrus female can be found below Figs. 2d–f. From left to right, encircled areas are paraventricular nucleus of the hypothalamus, anterior pituitary and ventral subiculum. **p < 0.01; *p < 0.05; #p < 0.10
