Table 2 Changes in cognitive performance after a 12-week MDCT intervention
Baseline | 3 months | P value | |
|---|---|---|---|
Overall cognition | |||
MMSE | 27.35 ± 2.23 | 27.06 ± 2.97 | 0.589 |
MoCA | 22.47 ± 4.47 | 21.88 ± 4.29 | 0.347 |
Memory | |||
HVLT-R immediate recall Trial 1 | 5.53 ± 1.74 | 4.94 ± 1.85 | 0.106 |
HVLT-R immediate recall Trial 2 | 7.18 ± 1.78 | 6.82 ± 1.55 | 0.463 |
HVLT-R immediate recall Trial 3 | 7.88 ± 1.80 | 8.00 ± 1.23 | 0.805 |
HVLT-R immediate recall total | 20.59 ± 4.77 | 19.76 ± 3.62 | 0.456 |
HVLT-R delayed recall | 5.12 ± 2.90 | 5.35 ± 2.93 | 0.753 |
HVLT-R retention (%) | 59.94 ± 33.82 | 63.91 ± 34.06 | 0.656 |
HVLT-R recognition discrimination Index | 8.12 ± 3.04 | 7.76 ± 3.58 | 0.231 |
Speed of processing | |||
Trail Making Test Part A (s) | 79.06 ± 48.57 | 76.18 ± 39.76 | 0.600 |
Visuospatial ability | |||
BVMT-R immediate recall total score | 18.35 ± 7.83 | 16.53 ± 8.74 | 0.286 |
BVMT-R delayed recall score | 6.88 ± 3.50 | 6.88 ± 3.84 | 1.000 |
Language | |||
Verbal Category Fluency | 16.59 ± 4.05 | 16.65 ± 4.51 | 0.956 |
Attention and working memory | |||
Digit Span total score | 15.47 ± 4.35 | 16.24 ± 3.44 | 0.389 |
Space Span total score | 13.41 ± 2.83 | 13.41 ± 3.94 | 1.000 |
Executive function | |||
Stroop-word | 65.94 ± 10.18 | 65.88 ± 10.02 | 0.968 |
Stroop-colour | 51.75 ± 9.42 | 53.06 ± 7.59 | 0.402 |
Stroop- Color-Word | 24.88 ± 7.44 | 24.75 ± 8.13 | 0.943 |
Golden’s Interference Score | −3.94 ± 7.08 | −4.44 ± 7.67 | 0.764 |
Reasoning | |||
Modified Picture Completion | 7.41 ± 1.66 | 6.88 ± 1.76 | 0.058 |