Fig. 3: Distribution of enrichment for association with schizophrenia or bipolar disorder across expression deciles.
From: Dynamic expression of genes associated with schizophrenia and bipolar disorder across development

Gene sets ranked by prefrontal cortical expression during Early Midfetal 1 (a), Early Infancy (b, c) and Late Childhood (d, e) were tested for enrichment for association with schizophrenia (a, b d) or bipolar disorder (c, e). All expressed genes were divided into ten equal groups ranked by their expression. Points represent −log10(P) sgn(β), where P is uncorrected following gene-set enrichment analysis and β is the corresponding regression coefficient. Dotted lines delimit significance thresholds following correction for ten analyses