Fig. 3: Interaction effects of Group × methylphenidate (MP) Challenge between cocaine use disorder (CUD) and healthy controls (HC). | Translational Psychiatry

Fig. 3: Interaction effects of Group × methylphenidate (MP) Challenge between cocaine use disorder (CUD) and healthy controls (HC).

From: Expectation effects on brain dopamine responses to methylphenidate in cocaine use disorder

Fig. 3

CUD has blunted responses to MP in putamen, caudate, and nucleus accumbens as compared to HC. The SPM images were superimposed onto T2-weighted magnetic resonance images in coronal (left upper) and sagittal (right upper) views. The color bar indicates t score values. Red represents the highest value and dark violet represents the lowest value. The bar chart showed DA release (PL–MP) in striatal regions in CUD and HC

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