Table 4 LDSR results for TS whole cohort and brain volume overlap

From: Concordance of genetic variation that increases risk for Tourette Syndrome and that influences its underlying neurocircuitry

Trait 1

Trait 2

rg

SE

95% CI

p-value

TS

Intracranial volume

−0.122

0.075

−0.269–0.025

0.106

Accumbens

−0.428

0.582

−1.568–0.712

0.462

Amygdala

–

–

–

–

Caudate

−0.037

0.087

−0.208–0.134

0.672

Hippocampus

−0.015

0.097

−0.205–0.175

0.878

Pallidum

−0.002

0.106

−0.21–0.206

0.983

Putamen

−0.023

0.091

−0.201–0.155

0.801

Thalamus

−0.227

0.12

−0.462–0.008

0.059*

  1. TS Tourette’s syndrome, CI confidence interval, Bonferroni corrected p-value = 0.05/48 = 1.042 × 10−3
  2. *Trending significance (p < 0.1)
Back to article page