Table 2 Results of Western blotting analysis of LCLs

From: Proteomic analysis of lymphoblastoid cell lines from schizophrenic patients

Spot No.

Candidate marker

1st sample set (CON n = 30, SCZ n = 30)

2nd sample set (CON n = 30, SCZ n = 30)

Combinede (CON n = 60, SCZ n = 60)

FCa

t-test P-valueb

Logistic regression analysis

FC

t-test P-value

Logistic regression analysis

FC

t-test P-value

Logistic regression analysis

OR

P-value

AUC

OR

P-value

AUC

OR

P-value

AUC

1

KIF11

1.31

0.284

(S)

2.10

0.289

0.63

            

2

HSPA4L

0.62

0.017

(W)

0.50

0.029

0.64

0.73

0.015

(W)

0.05

0.021

0.65

0.65

<0.001

(W)

0.59

0.03

0.61

3

HSP90AB1

1.12

0.390

(S)

1.45

0.384

0.57

            
 

PDXDC1

1.10

0.604

(S)

1.15

0.598

0.49

            

4

VPS35

0.88

0.295

(S)

0.39

0.296

0.55

            

5, 6, 7

MX1

1.39

0.006

(S)

9.26

0.011

0.72

1.32

0.006

(W)

12.76

0.012

0.68

1.35

<0.001

(W)

10.32

<0.001

0.70

8

LCP1

1.04

0.791

(S)

1.07

0.787

0.54

            

9

HARS

1.09

0.588

(S)

1.55

0.582

0.57

            

10

GLRX3

0.74

0.002

(W)

0.05

0.006

0.73

1.12

0.103

(S)

13.31

0.106

0.61

0.88

0.073

(S)

0.33

0.08

0.55

11

UROD

0.77

0.010

(S)

0.24

0.018

0.73

1.03

0.824

(W)

1.17

0.828

0.54

0.85

0.118

(S)

0.60

0.12

0.59

12

PPA1

0.99

0.953

(S)

0.97

0.952

0.50

            

13

ANXA5

0.88

0.105

(W)

0.32

0.109

0.61

            

14

MAPRE1

0.76

0.009

(S)

0.20

0.015

0.69

1.18

0.010

(S)

95.47

0.015

0.68

0.89

0.182

(S)

0.57

0.19

0.51

 

EFHD2

0.99

0.908

(S)

0.95

0.906

0.47

            
 

TBCB

0.68

0.024

(W)

0.20

0.034

0.66

0.95

0.628

(S)

0.68

0.622

0.57

0.82

0.035

(S)

0.36

0.04

0.60

15

UCHL1

0.97

0.919

(S)

0.99

0.917

0.54

            

16

APRT

0.59

0.248

(W)

0.90

0.356

0.49

            

17

IGHM

1.80

0.037

(W)

5.03

0.050

0.63

0.71

0.336

(W)

0.98

0.336

0.49

0.80

0.466

(S)

0.98

0.46

0.45

18

GART

0.75

0.022

(S)

0.15

0.031

0.66

0.73

0.002

(S)

0.02

0.005

0.74

0.74

<0.001

(W)

0.08

<0.001

0.70

19

EEF1G

1.16

0.154

(S)

2.35

0.158

0.65

            

20

LACTB2

1.10

0.358

(S)

1.76

0.356

0.56

            
 

TATDN1

1.14

0.195

(W)

2.58

0.210

0.57

            
  1. FC fold change, OR odds ratio (SCZ/CON), AUC the area under the receiver operating characteristic curves, Combined combined results of 1st sample set and 2nd sample set
  2. aFC = the ratio of the average intensity (SCZ/CON)
  3. bt-test P-value: the differentially expressed proteins were determined by Student’s t-test (S) or Welch’s t-test (W) (unpaired, two tailed)
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