Fig. 2: Effects of interventions on prolactin, citalopram and tryptophan levels. | Translational Psychiatry

Fig. 2: Effects of interventions on prolactin, citalopram and tryptophan levels.

From: Measuring endogenous changes in serotonergic neurotransmission with [11C]Cimbi-36 positron emission tomography in humans

Fig. 2

Time on the x-axis is referenced to the time of [11C]Cimbi-36 injection. a Plasma prolactin levels relative to time of [11C]Cimbi-36 injection. **p < 0.01 indicates Bonferroni-corrected post-test between groups (citalopram/pindolol versus ATD as well as placebo groups) in a 2-way ANOVA of prolactin concentration with time and treatment as main effects. Normal interval for plasma prolactin: 70-440mIU/L. b Serum citalopram concentrations relative to time of [11C]Cimbi-36 injection. Citalopram was given intravenously for one hour starting 30 minutes before time of injection. c. Plasma tryptophan levels relative to time of [11C]Cimbi-36 injection. ***p < 0.001 indicate Bonferroni-corrected post-test between groups (ATD versus citalopram/pindolol as well as placebo groups) in a 2-way ANOVA of tryptophan concentrations with time and treatment as main effects

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