Table 1 Summary of data for demographical and clinical data (longitudinal study)

From: Abnormal development of early auditory processing in 22q11.2 Deletion Syndrome

 

TD participants T1 (N = 14)

TD participants T2 (N = 14)

Carriers T1 (N = 16)

22q11.2DS carriers T2 (N = 16)

Age (mean age ± s.d.)

12.1 ± 1.3

15.6 ± 1.6

11.4 ± 1.9

15.3 ± 1.9

Gender (M/F)

8/6

 

12/4

 

Full-scale IQ (mean ± s.d.)a

111.6 ± 16.2

110.5 ± 14.2

74.8 ± 8.7

75.9 ± 12.8

DICA (N)

NA

NA

ADHD (7), Phobia (2), GAD (5), Encopresis (3), ODD (2), MDD (1)

ADHD (8), Phobia (3), GAD (4), MDD (1)

Antipsychotic treatment (N)

NA

NA

1

0

Antidepressant treatment (N)

  

0

2

Methylphenidate (N)

  

5

2

SIPS (mean±s.d.; range)

    

Positive

NA

NA

0.9 ± 1.4; 0–6

0.6 ± 1.1; 0–5

Negative

NA

NA

1.5 ± 1.3; 0–5

2 ± 1.2; 0–4

Disorganization

NA

NA

0.8 ± 1.2; 0–4

1 ± 1.2; 0–4

Generalized

NA

NA

0.8 ± 1.2; 0–5

0.9 ± 1; 0–4

  1. TD typically developing, DICA Diagnostic Interview for Children and Adolescents, ADHD attention deficit hyperactivity disorder, ODD oppositional defiant disorder, MDD major depressive disorder, GAD generalized anxiety disorder
  2. aThe full scale IQ did not significantly differ in the 22q11.2 deletion carriers (t = −0.5, d.f. = 14, p-value = 0.5) or the typically developing group (t = −1.1, d.f. = 10, p-value = 0.2) between T1 and T2