Fig. 4: Specific lipid species are differently regulated in the dorsal and ventral hippocampus by corticosterone.
From: Differential lipid composition and regulation along the hippocampal longitudinal axis
a Lipidome profile of dorsal and ventral hippocampus from adult rats submitted to daily injections of corticosterone (CORT) compared with vehicle-treated animals (VEH). The heatmap represents all lipid species detected by LC-MS in macrodissected tissue. Lipids were classified per total acyl carbons and degree of unsaturation, respectively. For additional lipid nomenclature, see Methods section. Values represented as average fold-change of individual species in dorsal and ventral hippocampus of CORT animals, normalized to VEH (only statistically significant values shown (p < 0.05), N = 9 for dorsal hippocampus of VEH; N = 10 for remaining groups). Results were compared using two-tailed Student’s t test. b A ventral/dorsal hippocampus ratio for each lipid species detected, per animal, was calculated in adult rats injected with VEH (gray) or CORT (red) (mean ± SEM, N = 9 for VEH; N = 10 for CORT). *p < 0.05, **p < 0.01, and ***p < 0.001 in two-tailed Student’s t test
