Table 3 Potential cut-off values of BDNF with corresponding sensitivity and specificity

From: Brain-derived neurotrophic factor as a possible predictor of electroconvulsive therapy outcome

 

Percentile

BDNF

Sensitivity

Specificity

Youden-index

Remission

20

11.8

0.2

0.9

0.2

30

15.2

0.4

0.9

0.2

40

16.5

0.5

0.8

0.3

50

17.9

0.6

0.7

0.3

60

19.8

0.7

0.6

0.2

70

21.1

0.8

0.4

0.2

80

23.6

0.8

0.2

0.1

Response

20

11.8

0.2

0.9

0.1

30

15.2

0.3

0.9

0.2

40

16.5

0.4

0.8

0.3

50

17.9

0.6

0.8

0.3

60

19.8

0.6

0.6

0.2

70

21.1

0.7

0.4

0.1

80

23.6

0.8

0.2

0.0

  1. Youden index = sensitivity + specificity – 1
  2. BDNF brain-derived neurotrophic factor level in ng/ml