Fig. 1: Effects of FMT on behavioral function and amyloid plaque in Tg mice. | Translational Psychiatry

Fig. 1: Effects of FMT on behavioral function and amyloid plaque in Tg mice.

From: Fecal microbiota transplantation alleviated Alzheimer’s disease-like pathogenesis in APP/PS1 transgenic mice

Fig. 1

a Escape latency of mice for 5 consecutive days in Morris water maze test. b Representative swimming tracks of mice in Morris water maze test. c Frequency of crossing the platform of mice in Morris water maze test. d Detention time in target quadrant in Morris water maze test. e Discrimination index of the object recognition test. Error bars indicate SEM; n = 6–8 for each group. *P < 0.05 vs. WT group, **P < 0.01 vs. WT group, #P < 0.05 vs. Tg group. f Representative photographs of Congo red staining in the cortex and hippocampal regions (CA1, CA3, and DG). CA, cornu ammonis; DG, dentate gyrus; magnification ×400. Scale bar = 50 µm. g The level of Aβ40 in the brain. h The level of Aβ42 in the brain. i Western blot analysis of p-Tau expression. j Quantitative analysis ratio of p-Tau/β-actin, the reference value of the p-Tau/β-actin was the ratio of the WT group. Error bars indicate SEM; n = 4–6 for each group. *P < 0.05 vs. WT group, **P < 0.01 vs. WT group, #P < 0.05 vs. Tg group, ##P < 0.01 vs. Tg group

Back to article page